After recently dispatching Richards Bay 3-0 in their last meeting, Mamelodi Sundowns are back in action three days later with the league title still firmly in their sights.
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Golden Arrows host Stellenbosch, Sekhukhune visit Magesi while SuperSport welcome Chippa in three of five Betway Premiership matches taking place on Saturday.
We take a look at a few things Kaizer Chiefs will need to get right in order to grab an unlikely victory over their Soweto rivals on Saturday afternoon.
Bradley Cross is hopeful about participating in his Soweto Derby debut.
Orlando Pirates captain Innocent Maela is confident his side can still lift the Betway Premiership trophy at the end of the season.
Orlando Pirates coach Jose Riveiro has reflected on the significance of the Soweto Derby and its impact on South African football.
Kaizer Chiefs and Orlando Pirates have been dealt a major blow with some of their key players set to miss out on the Soweto Derby showdown due to suspension.
Kaizer Chiefs head coach Nasreddine Nabi says his team are pumped up to win beat rivals Orlando Pirates and win the second Soweto derby of the season.
Mamelodi Sundowns head coach Miguel Cardoso was delighted to see his side record a comfortable 3-0 Betway Premiership win over Richards Bay on Wednesday.
Orlando Pirates coach Jose Riveiro admits his team was second best to Sekhukhune United in their 1-0 Betway Premiership loss on Wednesday night.