Jadon Sancho and Marcus Rashford fired Manchester United to a memorable first win under Erik ten Hag as bitter rivals Liverpool were beaten 2-1 on a night of protests against the Glazer family.
Jesus claimed his first Gunners goals since his summer switch from Manchester City by netting twice in last weekend's 4-2 Premier League success over Leicester.
United States manager Gregg Berhalter has backed "fighter" Christian Pulisic to prove his worth as speculation continues over the Chelsea forward's future.
Liverpool defender Virgil Van Dijk insists a disappointing start does not mean they head to Old Trafford looking to make a statement against a struggling Manchester United side.